Honso Select is manufactured by Honso Pharmaceutical Co. in Nagoya, Japan under pharmaceutical GMP standards and all Honso Select products are thoroughly tested for key herbal constituents, heavy metals and purity. Honso Pharmaceutical Co., has a strong reputation as one of the most highly regarded facilities for producing quality, effective herbal products surpassing standards set forth by Japanese Ministry of Health and Welfare. Which is why we work directly with them to produce our Honso Select brand of products.